ea0063p734 | Pituitary and Neuroendocrinology 2 | ECE2019
Storr Helen L
, Shah Nalini
, Wojna Judi
, Han Kevin
, Roughton Michael
, Pierre Combes Francois
, Pultar Philippe
, Savage Martin O
Background: In children, Cushings disease (CD) presents with a combination of weight gain and slowed linear growth. First-line pituitary surgery is the treatment of choice for most patients. In paediatric patients, the transsphenoidal surgical success rate is 60%98% when performed by an expert pituitary surgeon. There is a need for additional pharmacological interventions to control hypercortisolaemia, which are currently limited, in children and adolescents. In ph...